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Results 1 to 25 of 1896

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Characterization of a novel cyclin-dependent kinase 1 inhibitor, BMI-1026SEONG, Yeon-Sun; MIN, Changhee; LI, Luowei et al.Cancer research (Baltimore). 2003, Vol 63, Num 21, pp 7384-7391, issn 0008-5472, 8 p.Article

AZ703, an lmidazo[1,2-a]pyridine inhibitor of cyclin-dependent kinases 1 and 2, induces E2F-1-dependent apoptosis enhanced by depletion of cyclin-dependent kinase 9DONGPO CAI; BYTH, Kate F; SHAPIRO, Geoffrey I et al.Cancer research (Baltimore). 2006, Vol 66, Num 1, pp 435-444, issn 0008-5472, 10 p.Article

Cyclin-dependent kinase pathways as targets for cancer treatmentSHAPIRO, Geoffrey I.Journal of clinical oncology. 2006, Vol 24, Num 11, pp 1770-1783, issn 0732-183X, 14 p.Article

In vitro and In vivo pharmacokinetic-pharmacodynamic relationships for the trisubstituted aminopurine cyclin-dependent kinase inhibitors olomoucine, bohemine and CYC202RAYNAUD, Florence I; WHITTAKER, Steven R; VALENTI, Melanie et al.Clinical cancer research. 2005, Vol 11, Num 13, pp 4875-4888, issn 1078-0432, 14 p.Article

Antitumor effects of vitamins K1, K2 and K3 on hepatocellular carcinoma in vitro and in vivoHITOMI, Misuzu; YOKOYAMA, Fumi; WATANABE, Seishiro et al.International journal of oncology. 2005, Vol 26, Num 3, pp 713-720, issn 1019-6439, 8 p.Article

CDK Inhibitors : Cell Cycle Regulators and BeyondBESSON, Arnaud; DOWDY, Steven F; ROBERTS, James M et al.Developmental cell. 2008, Vol 14, Num 2, pp 159-169, issn 1534-5807, 11 p.Article

Revving the Throttle on an Oncogene: CDK8 Takes the Driver SeatFIRESTEIN, Ron; HAHN, William C.Cancer research (Chicago, Ill.). 2009, Vol 69, Num 20, pp 7899-7901, issn 0008-5472, 3 p.Article

Retinal and peripheral nerve toxicity induced by the administration of a pan-cyclin dependent kinase (cdk) inhibitor in miceILLANES, Oscar; ANDERSON, Scott; NIESMAN, Michael et al.Toxicologic pathology. 2006, Vol 34, Num 3, pp 243-248, issn 0192-6233, 6 p.Article

AT7519, A novel small molecule multi-cyclin-dependent kinase inhibitor, induces apoptosis in multiple myeloma via GSK-3β activation and RNA polymerase II inhibitionSANTO, L; VALLET, S; CALABRESE, E et al.Oncogene (Basingstoke). 2010, Vol 29, Num 16, pp 2325-2336, issn 0950-9232, 12 p.Article

Genetic cooperation between p21Cip1 and INK4 inhibitors in cellular senescence and tumor suppressionQUEREDA, V; MARTINALBO, J; DUBUS, P et al.Oncogene (Basingstoke). 2007, Vol 26, Num 55, pp 7665-7674, issn 0950-9232, 10 p.Article

Transcriptional upregulation of p57 (Kip2) by the cyclin-dependent kinase inhibitor BMS-387032 is E2f dependent and serves as a negative feedback loop limiting cytotoxicityMA, Y; CRESS, W. D.Oncogene (Basingstoke). 2007, Vol 26, Num 24, pp 3532-3540, issn 0950-9232, 9 p.Article

Cdk1 is sufficient to drive the mammalian cell cycleSANTAMARIA, David; BARRIERE, Cédric; CERQUEIRA, Antonio et al.Nature (London). 2007, Vol 448, Num 7155, pp 811-815, issn 0028-0836, 5 p.Article

Meriolins, a new class of cell death -Inducing kinase inhibitors with enhanced selectivity for cyclin-dependent kinasesBETTAYEB, Karima; TIRADE, Oscar M; LIGER, Francois et al.Cancer research (Baltimore). 2007, Vol 67, Num 17, pp 8325-8334, issn 0008-5472, 10 p.Article

Phosphorylation of Sld2 and Sld3 by cyclin-dependent kinases promotes DNA replication in budding yeastZEGERMAN, Philip; DIFFLEY, John F. X.Nature (London). 2007, Vol 445, Num 7125, pp 281-285, issn 0028-0836, 5 p.Article

Nuclear export of the human cytomegalovirus tegument protein pp65 requires cyclin-dependent kinase activity and the Crm1 exporterSANCHEZ, Veronica; MAHR, Jeffrey A; ORAZIO, Nicole I et al.Journal of virology. 2007, Vol 81, Num 21, pp 11730-11736, issn 0022-538X, 7 p.Article

Clinical anticancer drug development: targeting the cyclin-dependent kinasesBENSON, C; KAYE, S; WORKMAN, P et al.British journal of cancer. 2005, Vol 92, Num 1, pp 7-12, issn 0007-0920, 6 p.Article

CDK2-dependent phosphorylation of F0X01 as an apoptotic response to DNA damageHAOJIE HUANG; REGAN, Kevin M; ZHENKUN LOU et al.Science (Washington, D.C.). 2006, Vol 314, Num 5797, pp 294-297, issn 0036-8075, 4 p.Article

Gastric and pancreatic lesions in rats treated with a pan-CDK inhibitorRAMIRO-IBANEZ, Fernando; TRAJKOVIC, Dusko; JESSEN, Bart et al.Toxicologic pathology. 2005, Vol 33, Num 7, pp 784-791, issn 0192-6233, 8 p.Article

Preclinical activity of P276-00, a novel small-molecule cyclin-dependent kinase inhibitor in the therapy of multiple myelomaRAJE, N; HIDESHIMA, T; KIZILTEPE, T et al.Leukemia. 2009, Vol 23, Num 5, pp 961-970, issn 0887-6924, 10 p.Article

p27Kip1 Is a Microtubule-Associated Protein that Promotes Microtubule Polymerization during Neuron MigrationGODIN, Juliette D; THOMAS, Noémie; MOONEN, Gustave et al.Developmental cell. 2012, Vol 23, Num 4, pp 729-744, issn 1534-5807, 16 p.Article

CR8, a potent and selective, roscovitine-derived inhibitor of cyclin-dependent kinasesBETTAYEB, K; OUMATA, N; ECHALIER, A et al.Oncogene (Basingstoke). 2008, Vol 27, Num 44, pp 5797-5807, issn 0950-9232, 11 p.Article

p27Kip1 localization depends on the tumor suppressor protein tuberinROSNER, Margit; FREILINGER, Angelika; HANNEDER, Michaela et al.Human molecular genetics (Print). 2007, Vol 16, Num 13, pp 1541-1556, issn 0964-6906, 16 p.Article

Involvement of cAMP in nerve growth factor-triggered p35/Cdk5 activation and differentiation in PC 12 cellsCHEN, Mei-Chih; HO LIN; HSU, Fu-Ning et al.American journal of physiology. Cell physiology. 2010, Vol 68, Num 2, issn 0363-6143, C516-C527Article

Infrequent epigenetic dysregulation of CIP/KIP family of cyclin-dependent kinase inhibitors in multiple myelomaCHIM, C. S; LIANG, R; FUNG, T. K et al.Leukemia. 2005, Vol 19, Num 12, pp 2352-2355, issn 0887-6924, 4 p.Article

Design, synthesis, and testing of an 6-0-linked series of benzimidazole based inhibitors of CDK5/p25JAIN, Prashi; FLAHERTY, Patrick T; SHUYAN YI et al.Bioorganic & medicinal chemistry. 2011, Vol 19, Num 1, pp 359-373, issn 0968-0896, 15 p.Article

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